关于固氮酶固氮活性中心的结构问题,我国化学家先后提出过具有独特见解的“福州模型”(M Fe_8S_7)和由“厦门模型”修订而成的“综合模型”(M_oFe_6S_6L_2)。“福州模型”和“综合模型”有某些共同的观点,即认为:固氮酶在固氮反应时必须具有鸟窝开口式网兜状基本结构单元作为活性中心,而且具有M Fe_6S_6孪合重烷体的基本骨架。这种学术见解亟待化学合成予以验证。遗憾的是,这类钼铁混合簇孪合型重 As for the structure of nitrogenase active site, the chemists in our country have put forward “Fuzhou Model” (M Fe_8S_7) and “Comprehensive Model” (M_oFe_6S_6L_2) revised from “Xiamen Model” with unique insights. The Fuzhou Model and the Integrated Model share some common viewpoints that the nitrogenase must have an open network structure as the active center in the nitrogen fixation reaction and must have the M Fe_6S_6 twin heavy alkane Basic skeleton. This academic insight needs to be verified by chemical synthesis. Unfortunately, this type of molybdenum iron mixed cluster twin type heavy