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本研究于1984年10月至1987年9月应用Norplant皮下埋植剂1470人(其中Nor-Plant-Ⅰ1169人,Norplant-Ⅱ301人)控制生育。12个月和24个月的避孕效果:累积的妊娠率分别为0.2%和0.3%,持续使用率分别为96.5%和86.2%。主要副反应:月经不规则是终止使用的主要原因;但总失血量不多。Norplant埋植剂使用1年和2年后测定血红蛋白均值略有升高;血压无变化;体重略有增加。埋植剂的放置和取出易于掌握,在1470名使用者中未发生感染或其他并发症,使用安全。由于其妊娠率低和不可能脱落及其高度可逆性,深为受试者所欢迎。
This study from October 1984 to September 1987 application Norplant subcutaneous implants 1470 people (including Nor-Plant-1169 people, Norplant-Ⅱ 301) to control fertility. Contraceptive effects at 12 months and 24 months: The cumulative pregnancy rates were 0.2% and 0.3% respectively, with sustained rates of 96.5% and 86.2%, respectively. The main side effects: Irregular menstruation is the main reason to discontinue use; but the total amount of blood loss is small. Norplant implants showed a slight increase in mean hemoglobin after 1 year and 2 years; no change in blood pressure; slight weight gain. The placement and removal of implants is easy to grasp and safe for use without infection or other complications among 1470 users. Because of its low pregnancy rate and the possibility of shedding and its highly reversible, deep subjects are welcome.