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用减毒病毒传递抗原 ,通常能获得对疫苗的最佳免疫应答。虽然减毒病毒通常对健康接受者几乎不会造成任何问题 ,但是却能在免疫损害者中引起感染。法国科学家已研制了可消除这种担扰的新型肿瘤疫苗的载体。 研究者将志贺毒素 B亚单位 ( STB)融合至源于小鼠癌细胞的肿瘤肽 P81
With an attenuated virus delivering the antigen, the best immune response to the vaccine is usually obtained. Although attenuated viruses generally cause few problems to healthy recipients, they can cause infections in immunocompromised patients. French scientists have developed a carrier of a new type of oncology vaccine that will eliminate this problem. Researchers fused Shiga toxin B subunit (STB) to tumor peptide P81 derived from mouse cancer cells