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本研究将1982年1月到1983年12月41～70岁,无肾病或其他恶性肿瘤和化疗史的45例Ⅱ、Ⅲ期宫颈癌病人,随机分为二组:25例接受单纯放疗者中Ⅱb期15人、Ⅲb期10人,除一例为腺癌外均为鳞癌;20例接受放疗同时给顺氯氨铂(Cis-DPP)静脉注射者中Ⅱb期17人、Ⅲa期2人、Ⅲb期1人,均为鳞癌。放疗为盆腔外照射4,000cGy(编者注。1cGy=1rad),每周给1,000cGy,分四天,每天给250cGy。外照射结束后休息7天开始腔内镭疗,Ⅱ期病人给二次镭疗,一次给3,500mg/hr,另一次给2,500-3,000mg/hr,二次间隔7～10天。Ⅲ期病人给一次镭疗,总量为4,000mg/hr。放射化疗组自照射的第一天开始每周给Cis-DPP25mg/m~2静注,同时给以镇吐药,直到镭疗结束。
This study from January 1982 to December 1983 in 41 to 70 years old, no history of nephropathy or other malignancies and chemotherapy in 45 cases of stage Ⅱ, Ⅲ cervical cancer patients were randomly divided into two groups: 25 patients received simple radiotherapy Ⅱ b of 15, Ⅲ b of 10, except for one case of adenocarcinoma are squamous cell carcinoma; 20 cases received radiotherapy while cisplatin (Cis-DPP) intravenous injection in 17 patients Ⅱ b, Ⅲ a period of 2, Ⅲ b period 1, are squamous cell carcinoma. Radiotherapy was 4,000 cGy for extra-pelvic irradiation (Editor’s Note 1 cGy = 1 rad) giving 1,000 cGy weekly for four days giving 250 cGy daily. 7 days after the end of external irradiation began radiotherapy within the lumen, Ⅱ patients with secondary laser therapy, once to 3,500mg / hr, another to 2,500-3,000mg / hr, the second interval of 7 to 10 days. Patients with stage III radiotherapy, the total amount of 4,000 mg / hr. Radiotherapy group from the first day of irradiation began weekly Cis-DPP25mg / m ~ 2 intravenous injection of antiemetic drugs, until the end of radium.