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背景:新疆的特殊之处在于是国内少数民族与汉族混杂聚集地,新疆地区目前尚无少数民族与汉族间活体肾移植有种族差异的明确报道。目的:比较新疆地区少数民族与汉族间活体肾移植的种族差异。方法:回顾性分析新疆地区1999/2010行活体肾移植受者的临床资料,并对移植前、后一般临床资料,以及移植后少数民族与汉族间移植肾存活率进行比较分析,将可能影响移植肾存活率的各种因素进行单因素分析。结果与结论:纳入随访资料完善者178例,其中少数民族131例,汉族47例。汉族组受者的移植肾存活率较少数民族组患者稍高,但差异无显著性意义。对可能影响长期移植肾生存的因素进行Cox单因素分析,显示急性排斥反应对移植肾生存有明显影响。提示新疆地区不同民族间接受同种民族活体肾移植的短中期移植肾存活率差异无显著性意义,急性排斥反应为影响移植肾存活的重要因素。
Background: The special feature of Xinjiang lies in the fact that ethnic minorities in China are mixed with Han ethnicity. There are no clear reports of racial differences in living donor kidney transplantation between ethnic minorities and Han nationality in Xinjiang. Objective: To compare the ethnic differences of living donor kidney transplantations between ethnic minorities and Han nationality in Xinjiang. Methods: The clinical data of 1999 renal transplant recipients from 1999 to 2010 in Xinjiang were analyzed retrospectively. The clinical data before and after transplantation and the survival rate of transplanted kidneys between ethnic minorities and Han after transplantation were comparatively analyzed. Single factor analysis of various factors of renal survival rate. RESULTS AND CONCLUSION: A total of 178 cases were included in the follow-up data, including 131 cases of minorities and 47 cases of Han nationality. The survival rate of renal transplant recipients in Han nationality group was slightly higher than that in minority ethnic group, but the difference was not significant. Cox univariate analysis of factors that may affect the long-term survival of renal allografts showed that acute rejection had a significant effect on the survival of renal allografts. The results suggest that there is no significant difference between the survival rates of short-and-medium-term allograft in different ethnic groups living in the same kind in Xinjiang. Acute rejection is an important factor affecting the survival of the allograft.