1　口炎患者 ,70岁 ,因原发性高血压病口服硝苯地平 2 0ｍｇ ,ｔｉｄ ,服药第 3天患者出现口腔疼痛 ,并逐日加重 ,影响进食和说话 ,舌颊腭区粘膜大片充血 ,水肿并有水泡、溃烂及浅溃疡形成 ,齿龈亦有增生 ,充血 ,出血及糜烂。给予对症治疗 ,症状不见好转 ,停用硝苯地平后症状、 1 stomatitis patient, 70 years old, oral nifedipine 20mg, tid due to essential hypertension, patients with oral pain on the 3rd day of medication, and day by day aggravating, affecting the eating and speaking, tongue and cheek palate area mucosal hyperemia, Edema and blisters, ulcers and the formation of shallow ulcers, gingival also have hyperplasia, congestion, bleeding and erosion. Given symptomatic treatment, the symptoms did not improve, disable the symptoms after nifedipine,