论文部分内容阅读
在以维生素 K 为辅助因子的羧化酶作用下,将谷氨酸残基羧化成γ羧基谷氨酸,与 Ca~(2+)鳌合可促成血液凝固。另一方面,维生素 K2、3环氧化物经环氧化物还原酶(VKOR)作用,去除环氧而成为维生素 K。维生素 K 缺乏会使血液凝结中重要的谷氨酸残基上的羧化作用受损。1940年,Kar Link
Under the action of carboxylase with vitamin K as a cofactor, the glutamic acid residues are carboxylated to γ-carboxyglutamate and chelated with Ca 2+ to promote blood coagulation. On the other hand, vitamin K2, 3 epoxide by the role of epoxide reductase (VKOR), remove the epoxy and become vitamin K. Vitamin K deficiency can impair carboxylation on important glutamate residues in blood clotting. In 1940, Kar Link