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兹对我院1994—1996年PD专病门诊中长期应用丙炔苯丙胺(deprenyl)治疗观察的30例(24例PD,6例PDS)进行回顾并复习文献。原有抗PD治疗药物不变,加用丙炔苯丙胺渐至每日10mg。以改良Webster计分表评价病情,按治疗前后进步率计算结果。本组大部分对肌强直、震颤、少动等有改善。其疗效与治疗前病程、病情程度无明确关系;对早期PD应用丙炔苯丙胺可推迟左旋多巴的应用。副反应少,且为暂时性的。较安坦、金刚烷胺、左旋多巴类易于耐受,不失为可选用的药物之一
We retrospectively review and review the literature of 30 patients (24 PD, 6 PDS) who were treated with mid-to-long-term deprenyl therapy in our department from 1994 to 1996. The original anti-PD treatment of the same, plus use of propargyl amphetamine gradually to 10mg daily. The modified Webster score table was used to evaluate the condition and the result was calculated according to the progress rate before and after treatment. Most of this group of muscle rigidity, tremor, less moving, etc. have improved. The efficacy and duration of treatment before treatment, no clear relationship between the severity of the application of propranolol in early PD can delay the application of levodopa. Less side effects, and is temporary. Than Anta, amantadine, levodopa class is easy to tolerate, after all, one of the optional drugs