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实验应用光镜与电镜技术,观察老年大鼠甲状腺组织学与超微结构变化,以及补肾中药对老年大鼠甲状腺形态学的影响。老年大鼠甲状腺滤泡以及滤泡上皮细胞有显著退行性变化。而补肾中药组大鼠甲状腺滤泡及滤泡上皮细胞退行性变化减轻,近似青年组。实验结果提示:补肾中药能改善甲状腺的老化,从而延缓老年大鼠下丘脑—垂体—甲状腺—胸腺轴的衰老。
Light microscopy and electron microscopy techniques were used to observe the histological and ultrastructural changes of thyroid glands in aged rats and the effects of kidney-tonifying herbs on the thyroid morphology of aged rats. There were significant degenerative changes in thyroid follicles and follicular epithelial cells in aged rats. However, the degenerative changes of thyroid follicles and follicular epithelial cells in the Bushen Chinese medicine group were similar to the young group. The experimental results suggest that: Bushen Chinese medicine can improve the aging of the thyroid gland and delay the aging of the hypothalamus-pituitary-thyroid-thymus axis in aged rats.