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目的:观察三金片对择期手术后留置导尿管患者免疫功能的影响及预防尿路感染的效果。方法:选取76例择期手术后留置导尿管的患者作为研究对象,随机分为对照组和观察组各38例,对照组予以环丙沙星胶囊口服,观察组予以三金片口服。2组均持续用药2周。观察2组用药前后免疫球蛋白Ig A、Ig G、Ig M水平的变化情况;记录拔管后24 h中段尿细菌阳性、中段尿常规阳性及尿路感染阳性情况;观察2组的不良反应情况。结果:2组治疗后Ig A、Ig G、Ig M均明显上升,与治疗前相比,差异均有统计学意义(P<0.05);2组Ig A、Ig G、Ig M比较,差异均有统计学意义(P<0.05)。观察组治疗后24 h中段尿细菌阳性率、中段尿常规阳性率及尿路感染阳性率均低于对照组(P<0.05)。观察组不良反应发生率为2.63%,低于对照组的15.79%,差异有统计学意义(P<0.05);观察组眩晕、头痛、食欲减退、恶心的评分均低于对照组,差异均有统计学意义(P<0.05)。结论:择期手术后留置导尿管的患者口服三金片能够提高机体免疫力,降低尿路感染的几率。
Objective: To observe the effect of three gold tablets on immune function in patients with indwelling catheter after elective surgery and to prevent urinary tract infection. Methods: A total of 76 patients with indwelling catheters undergoing elective surgery were enrolled in the study. They were randomly divided into control group and observation group, 38 cases in each group. Ciprofloxacin capsules were given orally in the control group, while the observation group was given orally in three tablets. 2 groups were continued medication for 2 weeks. The changes of immunoglobulin Ig A, Ig G and Ig M levels before and after treatment were observed. Positive bacteria in the middle 24 hours after extubation, urinary routine positive and urinary tract infection were recorded. Adverse reactions of the two groups were observed . Results: The levels of Ig A, Ig G and Ig M were significantly increased in both groups after treatment, which were significantly different from those before treatment (P <0.05). The differences of Ig A, Ig G and Ig M between the two groups were statistically significant There was statistical significance (P <0.05). The positive rate of urinary bacteria, the positive rate of urinary routine and the positive rate of urinary tract infection in the middle 24 hours after treatment in the observation group were lower than those in the control group (P <0.05). The incidence of adverse reactions in the observation group was 2.63%, which was lower than that in the control group (15.79%), the difference was statistically significant (P <0.05). The scores of dizziness, headache, loss of appetite and nausea in the observation group were lower than those in the control group Statistical significance (P <0.05). Conclusions: Oral administration of three gold tablets in patients with elective catheterization can improve immunity and reduce the risk of urinary tract infection.