1987～1989年间,报道了9例出生在瑞典哥德堡市的先天性缺陷(包括畸形及智力迟钝)儿童,这些儿童的母亲曾在怀孕期间定时服用苯二氮(艹卓)类药物。由于酗酒也可引起这些先天缺陷,现有资料并不能确定此类药物和所报道的先天性缺陷的因果关系。因此,有必要进一步深入调查。苯二氮(艹卓)类药物曾被认为能导致胎儿先天腭裂,但随后,这种看法已大大动摇,它们仍广泛地在孕期使用以减轻忧虑及治疗子痫与先兆子痫。 Between 1987 and 1989, nine children with congenital defects (including deformity and mental retardation) born in Gothenburg, Sweden, were reported to have their mothers regularly taking benzodiazepines during pregnancy. Due to alcoholism can also cause these birth defects, available information does not determine the causal relationship between such drugs and the reported congenital defects. Therefore, it is necessary to further investigate. Benzodiazepines were once thought to cause fetal cleft palate, but then this view has been greatly shaken, and they are still widely used during pregnancy to reduce anxiety and treat eclampsia and preeclampsia.