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对比研究咪唑安定、硫贲妥钠或依托咪酯配伍小剂量芬太尼和琥珀胆碱用于心脏手术病人麻醉诱导、插管前后心率、动脉压、心率-动脉收缩压乘积(RPP)、动脉dp/dr max、动脉舒张压时间指数与收缩压时间指数之比(DPTI/SPTI)的变化,结果表明硫贲妥钠诱导后心率加快,动脉dp/dt max下降,插管后心率及RPP明显上升。咪唑安定麻醉后循环功能无明显变化,依托咪酯组麻醉后仅动脉压有所下降。3组病人麻醉前后DPTI/SPTI均无明显变化。
To compare the effects of midazolam, thiopental or etomidate with low-dose fentanyl and succinylcholine on cardiac surgery, anesthesia induction, heart rate before intubation, arterial pressure, heart rate-artery systolic pressure product (RPP) dp / dr max, ratio of arterial diastolic time index to systolic pressure time index (DPTI / SPTI). The results showed that after the induction of thiopental sodium, the heart rate was increased and the dp / dt max of the artery decreased. The heart rate and RPP were obviously increased after intubation rise. Midazolam did not change the circulatory function after anesthesia, and only decreased arterial pressure after etomidate anesthesia. There was no significant difference in DPTI / SPTI between the three groups before and after anesthesia.