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采用小剂量~131Ⅰ与抗甲状腺药联合治疗80例甲状腺机能亢进症（Graves）患者。~131Ⅰ治疗前用抗甲状腺药治疗半年以上，停抗甲状腺药一周后服~131Ⅰ111～296MBq（3～8mCi），服~131I一周后又加服抗甲状腺药直到甲亢治愈为止，与服~131Ⅰ370～555MBq（10～15mCi）前后不用抗甲状腺药的传统疗法相比，联合疗法组1年后的治愈率为98．8％，无甲状腺机能低下病人发现，而传统疗法组1年后治愈率为72％，甲状腺机能低下发生率为6.7％，因此联合疗法的近期效果优于传统疗法。
Eighty patients with hyperthyroidism (Graves) were treated with low dose 131I and antithyroid drugs. ~ 131 Ⅰ treatment with anti-thyroid drugs for more than six months before treatment, stopping anti-thyroid drugs after a week to take ~ 131 Ⅰ 111 ~ 296 MBq (3 ~ 8mCi), taking ~ 131I a week later plus anti-thyroid drugs until hyperthyroidism cured, and service ~ 131 Ⅰ ~ 555MBq (10 ~ 15mCi) before and after anti-thyroid drugs compared to traditional therapies, the combination therapy group 1 year after the cure rate was 98.8%, no hypothyroidism patients found, while the traditional therapy group after 1 year cure rate was 72 %, The incidence of hypothyroidism was 6.7%, so the combined effect of the recent better than traditional therapies.