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目的探讨肝动脉介入治疗对复发性肝癌患者的临床疗效。方法选取收治的复发性肝癌患者76例,依据治疗方法不同分为观察组(39例)和对照组(37例)。两组患者均给予肝动脉插管化疗栓塞治疗,观察组在此基础上再给予经皮瘤内无水酒精注射治疗。比较两组患者临床疗效、Karnofsky评分以及白细胞下降程度。结果观察组患者总有效率为64.1%,对照组患者总有效率为51.4%,差异有统计学意义(P<0.05)。观察组患者治疗后Karnofsky评分总增加率为61.5%,对照组为51.4%,差异有统计学意义(P<0.05);观察组患者治疗后白细胞总下降率为28.2%,对照组为48.6%,差异有统计学意义(P<0.05)。结论肝癌复发性患者肝动脉介入治疗临床疗效确切,能够明显改善患者Karnofsky评分,减少白细胞降低程度,改善患者生活质量。
Objective To investigate the clinical effect of hepatic artery interventional therapy in patients with recurrent liver cancer. Methods Totally 76 patients with recurrent hepatocellular carcinoma (HCC) were selected and divided into observation group (39 cases) and control group (37 cases) according to different treatment methods. Two groups of patients were given hepatic arterial chemotherapy and embolization, the observation group on this basis and then given percutaneous intratumoral alcohol injection therapy. The clinical efficacy, Karnofsky score and leukopenia were compared between the two groups. Results The total effective rate was 64.1% in observation group and 51.4% in control group, the difference was statistically significant (P <0.05). The total increase rate of Karnofsky score was 61.5% in the observation group and 51.4% in the control group, the difference was statistically significant (P <0.05); the total decline rate of leukocyte in the observation group was 28.2% after treatment and 48.6% in the control group, The difference was statistically significant (P <0.05). Conclusion Hepatectomy in patients with recurrent hepatic artery interventional treatment of clinical efficacy is exact, can significantly improve the patient’s Karnofsky score, reduce the degree of leukopenia and improve patient quality of life.