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本文介绍了不同工艺处理的冠心舒(碱性冠心舒和中性冠心舒)的抗凝及降脂作用的差别。实验结果表明,碱性处理的冠心舒无论是抗凝还是降脂作用都明显地强于中性处理的冠心舒。对小鼠的抗凝作用以及对Triton WR-1339诱发的大鼠高胆固醇血症的降胆固醇作用,两种冠心舒的作用强度,在所试剂量范围内都随剂量的增加而增加;然而,对Triton WR-1339性高甘油三酯血症,两种冠心舒在所试剂量范围内,其作用强度并不明显随剂量的增加而增加。
This article describes the different process of Guanxin Shu (alkaline crown Xin Shu and Guanxinshu) anticoagulant and lipid-lowering effect of the difference. The experimental results show that the alkaline treatment Guanxusu whether anticoagulant or lipid-lowering effect was significantly stronger than the neutral treatment Guanxin Shu. The anticoagulant effect on mice and the cholesterol-lowering effect on Tl-WR-1339-induced hypercholesterolemia in rats, the intensity of action of both Guanxinshu increased with increasing doses in the range of doses; however, , Triton WR-1339 hypertriglyceridemia, two kinds of coronary heart Shu in the range of doses, the intensity did not significantly increase with increasing doses.