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目的观察阿托伐他汀治疗高脂血症的临床效果。方法选择符合条件的原发高脂血症患者96例给予口服阿托伐他汀40 mg,晚餐后顿服,疗程12周,观察血脂变化。结果治疗12周后总胆固醇(TC),甘油酯(TG),低密度脂蛋白胆固醇(LDL-C)较治疗前有显著下降(P<0.01),高密度脂蛋白胆固醇(HDL-C)也明显升高(P<0.05),临床疗效显著,未发现明显不良反应。结论阿托伐他汀治疗高脂血症疗效显著,且不良反应小。
Objective To observe the clinical efficacy of atorvastatin in the treatment of hyperlipidemia. Methods A total of 96 patients with primary hyperlipidemia were given orally taken atorvastatin 40 mg and their meals were served after dinner for 12 weeks. The changes of blood lipids were observed. Results After 12 weeks of treatment, the levels of total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) were significantly lower than those before treatment (P <0.05), the clinical curative effect was significant, and no obvious adverse reaction was found. Conclusion Atorvastatin treatment of hyperlipidemia with significant effect, and adverse reactions.