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目的研究丽江产玛咖对半去势大鼠交配能力与阴茎勃起功能的影响,评价其作用效果。方法将♂大鼠随机分为6组,除正常对照组外,其余5组摘除右侧睾丸。正常对照、模型组(ig 10 m L·kg~(-1)生理盐水)、阳性对照组(sc 2 mg·kg~(-1)丙酸睾酮)及玛咖组(ig 0.64、0.32、0.16 g·kg~(-1)玛咖)给药32 d,进行交配和勃起实验,记录骑跨潜伏期、骑跨次数、勃起潜伏期并检测血清睾酮(T)、促间质细胞激素(LH)、促精子生成素(FSH)水平、前列腺和精囊腺脏器系数等指标。结果玛咖和丙酸睾酮能明显缩短半去势大鼠的骑跨潜伏期、勃起潜伏期,提高半去势大鼠的骑跨次数;显著降低血清中的LH水平,提高精囊腺脏器系数。结论玛咖具有提高半去势大鼠的交配能力和阴茎勃起功能的作用,其机制可能与调整失衡的血清性激素水平有关。
Objective To study the effects of Lijiang maca on the mating ability and penile erectile function in semi-castrated rats and to evaluate its effect. Methods ♂ rats were randomly divided into 6 groups, except for the normal control group, the remaining 5 groups removed the right testes. Normal control group, model group (ig 10 m L · kg -1 normal saline), positive control group (sc 2 mg · kg -1 testosterone propionate) and maca group (ig 0.64, 0.32, 0.16 g · kg ~ (-1) maca) for 32 d. The mating and erection experiments were performed. The latency of laps, the number of rides and erectile latency were recorded and the levels of serum testosterone (T), somatomedin (LH) Sperm production of sperm (FSH) levels, prostate and seminal vesicle organ coefficient and other indicators. Results Maca and testosterone propionate can significantly shorten the semi-castrated rats riding latency, erection latency and improve the semi-castrated rats riding times; significantly reduce the level of serum LH, semen organ index increased. Conclusion Maca can improve the mating ability and penile erectile function in semi-castrated rats. Its mechanism may be related to the adjustment of unbalanced serum sex hormones.