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目的分析免疫球蛋白及补体水平检测对A群轮状病毒性肠炎患儿的临床意义。方法选取2010年12月—2012年12月我院收治的A群轮状病毒性肠炎患儿56例(轮状病毒性肠炎组)及体检健康儿童56例(对照组),检测两组IgG、IgA、IgM及补体C3、C4水平。结果轮状病毒性肠炎组患儿IgG和IgA水平低于对照组(P<0.05);两组IgM、C3和C4水平比较,差异均无统计学意义(P>0.05)。结论 A群轮状病毒性肠炎患儿体液免疫功能方面存在着一定的紊乱现象,免疫球蛋白及补体水平检测可以有效地监测患儿体液免疫状况,为进一步的治疗提供科学依据。
Objective To analyze the clinical significance of detection of immunoglobulin and complement levels in children with group A rotavirus enteritis. Methods 56 cases (rotavirus enteritis group) and 56 healthy children (control group) of A group rotavirus enteritis admitted to our hospital from December 2010 to December 2012 were enrolled in this study. IgG, IgA, IgM and complement C3, C4 levels. Results The levels of IgG and IgA in children with rotavirus enteritis group were lower than those in control group (P <0.05). There was no significant difference in IgM, C3 and C4 levels between the two groups (P> 0.05). Conclusion There is a certain disorder in the humoral immune function of children with rotavirus A infection. The detection of immunoglobulin and complement levels can effectively monitor the humoral immune status in children and provide a scientific basis for further treatment.