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To examine the prevalence of Human papillomavirus and Chlamydia trachomatis DN A in cervical samples among women with normal and abnormal cervical cytology fro m La Plata, Argentina. Two hundred and seventy-nine women (200 with cervical ne oplasia or ICC and 79 women with normal cytology) provided cervical samples for the detection of HPV and C. trachomatis DNA by PCR-based assays. HPV DNA increa sed with the cervical lesion severity, ranging from 30%among women with normal cytology to 99-100%among women with HSIL or ICC. C. trachomatis DNA prevalence increased from low levels in women with normal cytology (11%) to 47%in those with HSIL, but was uncommon among ICC patients (20%)-. Among women with normal cytology, C. trachomatis prevalence was higher in HPV DNA positive (12.5%) tha n HPV DNA negative women (10.9%), but this difference was not significant. HPV prevalence in the general population is slightly higher than those reported for other developing countries. C. trachomatis DNA positivity was associated with a higher risk of both LSIL and HSIL lesions, but not with ICC.
To examine the prevalence of Human papillomavirus and Chlamydia trachomatis DN A in cervical samples among women with normal and abnormal cervical cytology fro m La Plata, Argentina. Two hundred and seventy-nine women (200 with cervical neoplasia or ICC and 79 women with normal cytology provided cervical samples for the detection of HPV and C. trachomatis DNA by PCR-based assays. HPV DNA increa sed with the cervical lesion severity, ranging from 30% among women with normal cytology to 99-100% among women with HSIL or ICC. C. trachomatis DNA prevalence increased from low levels in women with normal cytology (11%) to 47% in those with HSIL, but was uncommon among ICC patients (20%) -. Among women with normal cytology, C. trachomatis prevalence was higher in HPV DNA positive (12.5%) tha n HPV DNA negative women (10.9%), but this difference was not significant. HPV prevalence in the general population is slightly higher than those reported for other developing countries. C. trachomatis DNA p ositivity was associated with a higher risk of both LSIL and HSIL lesions, but not with ICC.