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多数学者认为,急性心肌梗塞(AMI)是在动脉硬化狭窄的基础上发生急性冠脉血栓所致。文献报告出现症状4小时内造影的322例中,87%示冠脉完全阻塞:手术时多数可以取出血栓。因此,在AMI早期使用溶血栓剂,可以减少或防止冠脉血栓引起的心肌报害。20多年前曾有静脉注入链激酶(SK)治疗AMI病人的报告,结果不一。但用SK注入冠脉窦治疗AMI7例,全部取得临床进步,其中两侧ECG转为
Most scholars believe that acute myocardial infarction (AMI) is caused by acute coronary thrombosis based on atherosclerosis stenosis. Of the 322 reported symptoms within 4 hours of presentation in the literature, 87% showed complete occlusion of the coronary arteries: most of the thrombus was removed during surgery. Therefore, the use of thrombolytic agents early in AMI can reduce or prevent myocardial damage caused by coronary thrombosis. The report of intravenous streptokinase (SK) treatment of AMI patients more than 20 years ago showed mixed results. However, injection of SK into the coronary sinus in 7 cases of AMI, all made clinical progress, in which the ECG on both sides turned