大容量全肺灌洗(W hole lung lavage,WLL)是在全麻双腔气管插管下,对全肺肺泡腔和支气管树进行大容量液体灌洗,清除吸入粉尘、炎性细胞、细胞因子、免疫反应产物、异物等,达到治疗肺部疾病的目的。自1967年Ram irez J[1]首次采用WLL治疗肺泡蛋白沉积症以来,经过近四十年临床应 In the general anesthesia double lumen endotracheal intubation, large-capacity whole-lung irrigation (Wlob lung lavage, WLL) is a large volume liquid lavage of the whole lung alveolar cavity and bronchial tree, removing inhaled dust, inflammatory cells, cytokines , Immune reaction products, foreign bodies, etc., to achieve the purpose of treatment of lung disease. Since Ramirez J [1] first adopted WLL in 1967 for the treatment of pulmonary alveolar proteinosis, after nearly forty years of clinical application