BCG超量深部接种局部发生异常强反应,临床处理甚感困难。最近,我们在全身抗痨治疗同时,改用RFP粉局部换药,收到较好效果。例1 男 6岁 3月前在厂医院行皮内BCG深部接种,半月后局部出现红肿硬结,此后破溃并伴低热,经青、链霉素注射和庆大霉素外敷无好转来诊。检查:体温37.8℃,精神差,左上臂注射部位硬结, BCG overdose deep abnormal local reaction, the clinical treatment is very difficult. Recently, we in the systemic anti-tuberculosis treatment at the same time, switch to the local RFP powder dressing, received good results. Example 1 Male 6 years old 3 months ago in the factory hospital intradermal BCG deep inoculation, local swelling and induration after half a month, then ulceration and fever, with green, streptomycin injection and gentamicin topical no referral. Check: body temperature 37.8 ℃, poor spirit, left upper arm injection site induration,