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为了对骨髓增殖性疾患(MPD)提出一种简单易行、具有预后意义的病理形态学分型,作者采用临床、组织学、形态学(塑料包埋技术)BMD计算机多参数分析,研究了2,500例已确诊或可疑的MPD病人,并根据骨髓增生占优势的细胞系,成熟程度,分布状态,巨核细胞的异常和纤维化程度,对MPD作了分型如下。1.真性红细胞增多症(PV) 根据骨髓增生的细胞成分,把PV病理分四个亚型,(1)经典的三系增生型(51%),伴有巨大巨核,
In order to propose a simple and prognostic pathomorphological classification of myeloproliferative disorders (MPD), the authors used clinical, histological and morphological (plastic-embedded) BMD computer multiparametric analysis to study 2,500 cases MPD has been diagnosed or suspected patients, and based on the proliferation of myeloproliferative cell lines, the degree of maturity, distribution, megakaryocyte abnormalities and degree of fibrosis, the MPD was classified as follows. 1. Polycythemia vera (PV) According to the cellular components of myeloproliferation, the PV pathology is subdivided into four subtypes, (1) the classic triplex (51%) with a large megakaryocyte,