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目的:探讨颅内动脉瘤破裂出血介入治疗后早期持续腰大池引流对脑血管痉挛(CVS)的影响。方法:对60例Hunt-Hess分级为Ⅲ级的颅内动脉瘤破裂出血患者行介入治疗,并将其随机分为观察组36例和对照组24例,观察组给予早期持续腰大池引流,对照组给予间断腰穿释放脑脊液,比较两组并发症发生情况及脑脊液红细胞和压力参数等相关指标。结果:观察组脑脊液中红细胞计数和脑脊液压力从术后第3天开始明显低于对照组(P<0.05),观察组CVS发生率明显低于对照组(P<0.05)。结论:动脉瘤介入治疗术后早期持续腰大池引流可有效防治CVS,值得临床推广应用。
Objective: To investigate the effect of continuous lumbar drainage on cerebral vasospasm (CVS) after intracranial aneurysm rupture hemorrhage after interventional therapy. Methods: Sixty patients with Hunt-Hess grade Ⅲ intracranial aneurysm rupture and bleeding were randomly divided into observation group (36 cases) and control group (24 cases). The observation group was given continuous laminectomy drainage and the control group Group was given intermittent lumbar puncture release of cerebrospinal fluid, compared the incidence of complications and cerebrospinal fluid erythrocyte and pressure parameters and other related indicators. Results: The cerebrospinal fluid erythrocyte count and cerebrospinal fluid pressure in the observation group were significantly lower than those in the control group on the 3rd day after operation (P <0.05). The incidence of CVS in the observation group was significantly lower than that of the control group (P <0.05). CONCLUSION: CVS can be effectively controlled by persistent lumbar drainage in the early postoperative period after interventional therapy of aneurysms, which is worthy of clinical application.