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目的:本文报告CEA、CA19-9、CA72-4三项肿瘤标志物,单项与联检诊断胃恶性肿瘤的临床价值。方法:应用免疫放射分析(IRMA)。结果:本文单项检测阳性率在70%以上,但以CA72-4阳性率最高(84.21%),次为CA19-9(75.43%)。作为单项应用首选CA72-4,次为CA19-9。全文仅4例三项均阴性(假阴性率为1.75%),故三项联检可使阳性率提高到98.25%。本文分三组双项组合检测,按双阳性分析,结果显示A组阳性率最高(61.84%),次为B组(51.31%),C组(48.24%)。结论:单项筛选检测,首选CA72-4,双项组合检测仍以CA72-4+CA19-9为宜,随访可按组织学类型选用。
Objective: This article reports CEA, CA19-9, CA72-4 three tumor markers, single and joint clinical diagnosis of gastric cancer. Methods: The application of immune radiation analysis (IRMA). Results: The positive rate of single detection in this article was over 70%, but the highest positive rate was CA72-4 (84.21%) and the second was CA19-9 (75.43%). As a single application preferred CA72-4, times as CA19-9. Full text only 4 cases were negative three (false negative rate was 1.75%), so the three joint examination can make the positive rate increased to 98.25%. According to double-positive analysis, the positive rate of group A was the highest (61.84%), followed by group B (51.31%) and group C (48.24%). Conclusion: Single screening test, the preferred CA72-4, double combination test is still CA72-4 + CA19-9 is appropriate, follow-up can be selected according to histological type.