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本文就纳洛酮对击剑运动员短时间剧烈运动前后机体免疫功能的影响进行了初步探讨,结果表明:1.运动前静脉注射纳洛酮后跑步4000米,外周血T细胞亚群的变化表现为CD_2~+细胞亚群百分率升高,CD_4~+CD_3~+比值下降。2.运动后外周血白细胞诱生干扰素的能力显著高于运动前,P<0.01。3.运动后NK细胞活性与白细胞吞噬百分率有下降的趋势,但吞噬指数显著增高。纳洛酮对外周血白细胞诱生干扰素的能力,NK细胞活性及白细胞吞噬功能均未见有明显影响。
In this paper, the effects of naloxone on the immune function of fencing athletes before and after intense short-term exercise were discussed. The results showed that: 1. After running naloxone intravenously for 4,000 meters, the changes of peripheral blood T cell subsets The percentage of CD-2~+ cell subsets increased, and the ratio of CD_4~+CD_3~+ decreased. The ability of peripheral blood leukocytes to induce interferon after exercise was significantly higher than before exercise, P<0.01.3.The percentage of NK cell activity and leukocyte phagocytosis decreased after exercise, but the phagocytic index increased significantly. Naloxone had no significant effect on the ability of interleukin to induce interferon, NK cell activity and leukocyte phagocytosis.