目的:探索结婚登记人群HIV/AIDS的流行情况,为开展新婚夫妇HIV/AIDS预防和阻断工作提供有效方法和科学依据。方法:采用流行病学现场研究方法进行研究。结果:结婚登记人群自愿检测HIV抗体有2532例,确认HIV抗体阳性28例,感染率为11.1‰。不同年龄、性别、婚姻状况、职业人群HIV抗体阳性率的差异有统计学意义(P<0.05),以31~40岁年龄组、男性、再婚者、经商人员、无业人员的HIV抗体阳性率居高。回顾性队列研究表明,静脉吸毒暴露者、不洁性行为暴露者感染HIV的危险度分别是其相对应非暴露者的114.091倍和109.087倍。非条件Logistic回归分析表明,结婚登记人群HIV/AIDS感染与婚姻状况、静脉吸毒史、不洁性行为史呈正相关,与性别、文化程度呈负相关。结论:结婚登记人群HIV/AIDS疫情呈散发,HIV在夫妻和母婴之间传播的可能性大,建议积极开展结婚登记人群HIV/AIDS自愿咨询检测工作,并建立法制化婚检制度。通过此项研究掌握了结婚登记人群HIV的感染率;通过干预,女性感染者对生育或不生育有了选择权;降低了目标人群HIV抗体阳性配偶间平行传播;降低了孕产妇HIV的感染和阳性孕产妇选择不生育,从而降低了HIV的母婴垂直传播;提高了HIV的母婴阻断率;提高了目标人群对艾滋病知识的普及率和行为形成率。 Objective: To explore the prevalence of HIV / AIDS among married people and provide an effective method and scientific evidence for the prevention and prevention of HIV / AIDS among newly married couples. Methods: Using epidemiological field research methods. Results: 2532 cases of HIV antibody were detected voluntarily in married population, 28 cases were positive for HIV antibody, the infection rate was 11.1% o. The positive rates of HIV antibody among different age, gender, marital status and occupational groups were statistically significant (P <0.05). The prevalence of HIV antibody among 31-40 age group, male, remarried, business man and unemployed high. Retrospective cohort studies have shown that the risk of HIV infection among intravenous drug users and those with unclean sexual behaviors is 114.091 and 109.087 times that of non-exposed non-exposed individuals, respectively. Non-conditional logistic regression analysis showed that the HIV / AIDS infection in marriage-registered population was positively correlated with marital status, history of intravenous drug abuse and history of unclean sexual behavior, and negatively correlated with gender and educational level. Conclusion: The HIV / AIDS epidemic among married people is likely to spread. HIV is highly likely to spread between husband and wife. It is suggested that HIV / AIDS voluntary counseling and testing should be carried out and a legalized premarital system should be established. Through this study, the HIV infection rate of married people in registration was grasped. By means of intervention, women infected had the option of having or not having children, reducing the parallel transmission of HIV antibody positive spouses in the target population, reducing the HIV infection of pregnant women and Positive pregnant women choose not to have childbirth, thus reducing the vertical transmission of HIV from mother to infant; increasing the maternal-child blocking rate of HIV; and increasing the target population’s HIV prevalence and behavior formation rate.