论文部分内容阅读
目的:分析和研究兰索拉唑与抗生素联合对酒精型消化溃疡的治疗效果。方法:选取2014年10月-2015年3月酒精型消化溃疡患者128例,将其随机分为药物联合组与单用兰索拉唑组,每组各有患者64例。单用兰索拉唑组患者给予单独兰索拉唑治疗;药物联合组患者给予兰索拉唑+抗生素治疗,将两组患者治疗结束后的效果、幽门螺杆菌清除率进行对比。结果:药物联合组患者治疗总疗效跟单用兰索拉唑组相比有显著差异P<0.05。两组患者幽门螺杆菌清除率相比较:药物联合组高于单用兰索拉唑组P<0.05。结论:酒精型消化溃疡患者应用兰索拉唑与抗生素联合治疗的效果显著,虽然单独兰索拉唑也能一定程度改善患者临床症状,清除幽门螺杆菌,但两种药物联用后在这方面疗效更为显著,值得推广。
Objective: To analyze and study the therapeutic effect of lansoprazole combined with antibiotics on alcoholic peptic ulcer. Methods: A total of 128 patients with alcoholic peptic ulcer were selected from October 2014 to March 2015, and randomly divided into drug combination group and lansoprazole group, with 64 patients in each group. Patients in the Lansoprazole group received lansoprazole alone. Patients in the drug combination group received lansoprazole plus antibiotics, and the effect of the two groups of patients after treatment and Helicobacter pylori eradication rate were compared. Results: The total curative effect of the combination group was significantly lower than that of the lansoprazole alone group (P <0.05). Helicobacter pylori eradication rates were compared between the two groups: the drug combination group was higher than the lansoprazole group alone (P <0.05). Conclusions: The combination of lansoprazole and antibiotics is effective in patients with alcoholic peptic ulcer. Although lansoprazole alone can also improve the clinical symptoms and eliminate Helicobacter pylori in patients, the combination of the two drugs in this aspect More significant effect, it is worth promoting.