论文部分内容阅读
目的:研究直径3厘米以上周围型肺癌血流动力学的螺旋CT(电子计算机断层扫描,Computed Tomography)动态增强扫描的特点。方法:选取我院收治的肿瘤直径>3 cm的周围型肺癌患者55例,肺部腺瘤(良性)患者10例,肺部炎性结节患者26例。分别进行螺旋CT动态增强扫描,记录其CT值、强化峰值(Peak enhancement,PH),绘制动态增强时间-密度曲线,计算并比较曲线最大增强线性斜率(steepes slope,SS)以及血流灌注量(blood perfusion,BP)。结果:肺部炎性结节患者的密度曲线在120 s达到最大值;肺癌患者的密度曲线至65 s达到高峰;胸腺瘤患者的密度曲线变化不明显。肺癌组PH平均值大于胸腺瘤组,差异有统计学意义(P<0.05);胸腺瘤组PH平均值小于肺部炎性结节组,差异有统计学意义(P<0.05);肺癌组SS和BP大于胸腺瘤组,差异有统计学意义(P<0.05);胸腺瘤组SS和BP小于肺部炎性结节组,差异有统计学意义(P<0.05)。结论:螺旋CT动态增强扫描能够反映直径3厘米以上周围型肺癌的血流动力学特点从而有助于在肺癌的诊断和鉴别诊断。
PURPOSE: To study the characteristics of dynamic contrast-enhanced computed tomography (CT) scan of hemodynamics of peripheral lung cancer over 3 cm in diameter. Methods: 55 cases of peripheral lung cancer with tumor diameter> 3 cm, 10 cases of pulmonary adenoma (benign) and 26 cases of pulmonary inflammatory nodules were selected in our hospital. Spiral CT dynamic contrast-enhanced scanning was performed. The CT value, peak enhancement (PH) and dynamic enhancement time-density curve were recorded. The maximum steepes slope (SS) and the amount of perfusion blood perfusion, BP). Results: The density curve of patients with inflammatory pulmonary nodules reached its maximum at 120 s. The density curve of lung cancer patients peaked at 65 s. The density curve of thymoma patients did not change significantly. The average value of PH in lung cancer group was higher than that of thymoma group (P <0.05), and the average value of PH in thymoma group was less than that in inflammatory lung nodule group (P <0.05). The lung cancer group SS (P <0.05). The levels of SS and BP in thymoma group were lower than those in inflammatory group with pulmonary tuberculosis (P <0.05). The difference was statistically significant (P <0.05). Conclusion: The spiral CT dynamic contrast-enhanced scan can reflect the hemodynamic characteristics of peripheral lung cancer more than 3 cm in diameter, which is helpful for the diagnosis and differential diagnosis of lung cancer.