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目的:探讨ras P21与胃癌生长速度之关系.方法:为在免疫组化的基础上探讨ras P21与胃癌生长速度之关系.作者设计了与过去文献不同的观察方法,不仅像过去文献那样观察胃癌之粘膜层之抗体表达,还分别观察粘膜下层、肌层、浆膜层及转移到局部淋巴或其他脏器癌细胞ras P21之表达,标本取自常观病理检查,均作H.E及ABC染色.结果:ras P21在胃癌细胞之检出率及反应强度在胃各层及局部淋巴转移的癌细胞中相似.早期胃癌ras P21检出率低于进展胃癌.结论:rasP21癌基因对胃癌之生长速度无明显影响.
Objective: To investigate the relationship between ras P21 and the growth rate of gastric cancer. Methods: To explore the relationship between ras P21 and the growth rate of gastric cancer based on immunohistochemistry. The author designed a different observation method from the previous literature, not only to observe gastric cancer as in the previous literature The mucosal layer of antibody expression, but also observed submucosa, muscularis, serosal layer and metastasis to regional lymphoid or other organ cancer cells ras P21 expression, specimens taken from the pathological examination, were HE and ABC staining. RESULTS: The detection rate and response intensity of ras P21 in gastric cancer cells were similar in gastric cancer cells and regional lymph node metastases. The detection rate of ras P21 in early gastric cancer was lower than that in advanced gastric cancer. Conclusion: The growth rate of rasP21 oncogene in gastric cancer No significant effect.