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细胞间通讯方式可分为间接与直接通讯方式,以体循环远程分泌、旁分泌和自分泌方式完成的调节方式为间接通讯,而以细胞间隙连接为途径进行的细胞间直接的信息交流为直接通讯。细胞间隙连接又称缝隙连接,是普遍存在于人和动物组织中的一种细胞连接形式。近年有一系列研究表明缝隙连接胞间通道的异常与糖尿病及其并发症的发生、发展密切相关,本文将就有关这方面的研究进展作一综述。
Intercellular communication can be divided into indirect and direct communication, to the systemic circulation of remote secretion, paracrine and autocrine methods to complete the regulation of indirect communication, and cell gap junctional approach for the direct exchange of information between cells for direct communication . Cell gap junction, also known as gap junction, is a form of cell junction commonly found in human and animal tissues. In recent years, a series of studies have shown that the gap junction intercellular channel abnormalities and diabetes and its complications are closely related, the development of this article will be reviewed in this regard.