本文验证了用Elisa检测钩端螺旋体病特异性IgM的敏感性与特异性。82例可疑钩端螺旋体病患者中阳性率为84.14％,比显凝试验高7％,其中血培养阳性者Elisa阳性率比显凝试验高15.71％。在可疑钩端螺旋体病患者中血培养与显凝试验皆阴性者共16例,除1例外Elisa全部阴性。58例发病3天内的钩端螺旋体病患者,Elisa阳性率可达44.82％,其中血培养阳性患者可高达50％。 This paper validates the sensitivity and specificity of Elisa for detection of leptospirosis-specific IgM. The positive rate of 82 suspicious leptospirosis patients was 84.14%, which was 7% higher than that of coagulation test, and the Elisa positive rate of blood culture positive was 15.71% higher than that of coagulation test. In suspicious leptospirosis patients blood coagulation test and coagulation tests were negative in a total of 16 cases, with 1 exception Elisa all negative. In 58 patients with leptospirosis within 3 days of onset, the positive rate of Elisa was 44.82%, of which 50% were positive in blood culture.