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采用放射免疫测定法研究了70例非应激性消化性溃疡患者的皮质醇分泌状态;并比较了患者与84例正常人的血清皮质醇浓度及其昼夜分泌节律。发现非应激性消化性溃疡血清皮质醇浓度明显高于健康对照组(P<0.01);然昼夜分泌节律相仿。结果提示,非应激性消化性溃疡有皮质醇分泌的明显异常。
Radioimmunoassay was used to study the cortisol secretion status in 70 patients with non-stress peptic ulcer. The serum cortisol concentration and its circadian rhythm were also compared between patients and 84 healthy controls. Found that non-stress peptic ulcer serum cortisol concentration was significantly higher than the healthy control group (P <0.01); However, similar circadian rhythm. The results suggest that non-stress peptic ulcer has a significant abnormal cortisol secretion.