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目的 :探讨SPECT/CT符合线路18F FDG显像在食管癌的诊断中的应用价值。方法 :19例食管癌患者行SPECT/CT符合线路18F FDG显像 ,患者禁食 6h以上 ,肘静脉注射18F FDG 185～ 2 96MBq。静注 60min后开始发射和X线CT透射扫描 ,然后进行符合线路PET连续采集 3 0min。图像经X线衰减校正和有序子集最大期望值法 (COSEM )叠代重建后 ,得到横断面、冠状面、矢状面三维断层图像及CT与FDGSPECT的融合图像。结果 :19例患者的18F FDGSEPCT显像图均显示食管部位有异常放射性浓聚灶 ,经病理证实 ,19处食管浓聚灶均为食管癌原发病灶。其中 5例为单发病灶 ,其余 14例并有他部位共 2 7个浓聚灶 ,经病理证实为远处转移病灶。 19例食管原发病灶摄取比值 (L/B)为 5 6± 2 3 ,转移灶摄取比值 (L/B)为 3 1± 1 7。与 19例18F FDGSPECT显像前CT检查结果比较 ,18F FDGSPECT共检出食管部位恶性病灶 19例 ,检出率为 10 0 % ,而CT仅检出 13例 ,检出率为 68 4%。 19例确诊有其他部位转移者为 14例 ,18F FDGSPECT检出 14例 ,检出率为 10 0 % ,而18F FDGSPECT显像前CT检查仅检出 6例 ,检出率为 42 9%。 15例手术治疗者18F FDGSPECT分期与临床病理分期一致 ,而常规检查对食管癌临床分期高估 2例 ,低估 7例 ,18F FDGSPECT显像改变了这
Objective: To investigate the value of SPECT / CT line 18F FDG imaging in the diagnosis of esophageal cancer. Methods: Nineteen patients with esophageal cancer underwent SPECT / CT 18F FDG imaging. The patients were fasted for more than 6 hours and 18F FDG 185-296 MBq were injected into the elbow vein. 60min after intravenous injection started and X-ray CT transmission scan, and then follow the line PET continuous collection 30min. After the images were iteratively reconstructed by X-ray attenuation correction and COSEM, the three-dimensional images of the cross-section, coronal plane and sagittal plane and the fusion image of CT and FDGSPECT were obtained. Results: The 18F FDGSEPCT images of 19 patients showed abnormal radioactive focus in the esophagus. The pathological examination confirmed that all 19 esophageal lesions were primary esophageal lesions. Among them, 5 cases were single lesions, and the remaining 14 cases had a total of 27 hematoma lesions in his area. The pathological findings were distant metastasis lesions. The ratio of primary esophageal lesion uptake (L / B) was 5 6 ± 2 3, and the ratio of uptake of metastasis (L / B) was 31 ± 1 7. Compared with the results of 19 cases of 18F FDGSPECT before CT, 18 cases of FDGSPECT were detected in 19 cases of malignant esophageal lesions, the detection rate was 10%, while CT only detected 13 cases, the detection rate was 68 4%. Among the 19 cases, 14 cases were diagnosed as having other metastasis, 14 cases were detected by 18F FDGSPECT, and the detection rate was 100%. Only 6 cases were detected by 18F FDGSPECT before CT, and the detection rate was 42.9%. The 18F FDGSPECT staging was consistent with clinicopathological stage in 15 cases of surgical treatment, while routine examination overestimated the clinical stage of esophageal cancer in 2 cases, underestimated in 7 cases, 18F FDGSPECT imaging changed this