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目的:评价马来酸依那普利叶酸片对H型高血压患者降压作用的临床疗效。方法:选择2014年10月—2015年10月收治的H型高血压患者104例,按照随机数字法将其分为对照组和观察组;对照组患者给予依那普利片治疗,观察组患者给予马来酸依那普利叶酸片治疗;评价两组患者治疗前后血压、血清高浓度半胱氨酸(HCY)水平的改善情况和不良反应的发生率。结果:两组患者治疗后血Hcy水平改善情况显著优于治疗前(P<0.05);治疗过程中,观察组患者不良反应的发生率为5.77%低于对照组为15.38%(P<0.05)。结论:马来酸依那普利叶酸片用于治疗H型高血压患者的疗效果较为显著,能快速改善血压水平。
Objective: To evaluate the clinical efficacy of enalapril maleate folic acid tablets in lowering blood pressure in Hypertensive patients. Methods: A total of 104 patients with H-type hypertension admitted from October 2014 to October 2015 were randomly divided into control group and observation group. Patients in the control group were treated with enalapril and patients in the observation group The administration of enalapril maleate folate tablets was performed. The improvement of blood pressure, serum high concentration of cysteine (HCY) and the incidence of adverse reactions were evaluated in both groups before and after treatment. Results: The improvement of blood Hcy level in both groups was significantly better than that before treatment (P <0.05). During the treatment, the incidence of adverse reactions in the observation group was 5.77% lower than that in the control group (15.38%, P <0.05) . CONCLUSIONS: Enalapril maleate folate tablets are particularly effective in the treatment of Hypertension patients and can rapidly improve blood pressure.