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目的探讨即刻治疗和延迟治疗对新诊断癫痫患者复发的影响。方法将2010年1月-2013年1月我院新诊断的126例癫痫病患者根据治疗前发作次数将患者分为即刻治疗组(≤3次)75例和延迟治疗组(>3次)51例,均予以合理的AEDs治疗。评定两组疗效,随访观察两组3、6、12、24个月的复发率。结果即刻治疗组总有效率明显高于延迟治疗组;即刻治疗组在随访各时点的复发率均显著低于延迟治疗组,在第3、6个月时差异尤为明显。结论对于治疗前发作次数≤3次的新诊断癫痫患者,即刻治疗较延迟治疗能取得更好的临床效果,复发率更低。但临床需根据患者具体特点做到个体化治疗,不能一概而论。
Objective To investigate the effect of immediate treatment and delayed treatment on the recurrence of newly diagnosed epileptic patients. Methods From January 2010 to January 2013, 126 newly diagnosed epilepsy patients in our hospital were divided into immediate treatment group (≤3 times) and delayed treatment group (≥3 times) according to the number of pre-treatment seizures Cases, are treated with reasonable AEDs. The curative effect of two groups were evaluated. The recurrence rates of the two groups were observed at 3,6,12,24 months. Results The total effective rate of the immediate treatment group was significantly higher than that of the delayed treatment group. The recurrence rate of the immediate treatment group was significantly lower than that of the delayed treatment group at the time of follow-up, especially at 3 and 6 months. Conclusions For newly diagnosed epilepsy patients with seizure frequency less than or equal to 3 before treatment, immediate treatment can achieve better clinical effect and delay rate of recurrence than delayed treatment. But the clinical needs to be based on the specific characteristics of patients to individual treatment, can not be generalized.