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以膀胱癌细胞株（BIU－87）为靶细胞，采用噻唑蓝（MTT）比色法进行了膀胱癌腔内化疗药物敏感试验及条件选择的实验研究。结果发现丝裂霉素C（MMC）、噻替哌（THT）、顺铂（DDP）对BIU－87细胞杀伤作用较明显，但在1mg／ml、2h作用条件下均未达到50％抑制率，需增加药物浓度和（或）延长作用时间。认为MMT、THT、DDP对BIU－87细胞的毒性作用与药物浓度和作用时间有关；为达到最大疗效，药物作用应足量，保留时间应尽可能长。
The bladder cancer cell line (BIU-87) was used as the target cell, and the chemosensitivity test and condition selection of bladder cancer were studied by MTT assay. The results showed that the killing effect of mitomycin C (MMC), thiotepa (THT) and cisplatin (DDP) on BIU-87 cells was obvious, but the inhibition rate reached 50% at 1mg / ml and 2h , Need to increase the drug concentration and (or) to extend the action time. The toxic effects of MMT, THT and DDP on BIU-87 cells are considered to be related to the drug concentration and the duration of action. In order to achieve the maximum therapeutic effect, the drug action should be sufficient and the retention time should be as long as possible.