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本文报告65例双炔失碳酯配伍d1-15甲基PGF_(2α)(以下简称PG)抗早孕结果并与33例丙睾配伍PG抗早孕结果进行比较。结果显示,双炔失碳酯组完全流产59例,占90%;不全流产3例,占5%;失败3例,占5%;总有效率95%。丙睾组完全流产27例,占82%;不全流产6例,占18%;总有效率100%。两组总有效率无显著差异;完全流产率无显著差异;但不全流产率有明显差异(P<0.05)。药流后点滴出血天数,双炔失碳酯组平均为8.1±5.0天;丙睾组平均为18.9±19.1天;两组有明显差别(P<0.05)。双炔失碳酯经阴道给药后无一例发生心、肝、肾功能变化。
This article reports 65 cases of anordrin ester with d1-15 methyl PGF_ (2α) (hereinafter referred to as PG) anti-early pregnancy results and 33 cases of pristine matching PG anti-pregnancy results were compared. The results showed that amethopterin group complete abortion in 59 cases, accounting for 90%; incomplete abortion in 3 cases, accounting for 5%; failure in 3 cases, accounting for 5%; total effective rate of 95%. 27 cases of complete abortion in the testis group, accounting for 82%; 6 cases of incomplete abortion, accounting for 18%; the total effective rate was 100%. The total effective rate was no significant difference between the two groups; complete abortion rate was no significant difference; but incomplete abortion rate was significantly different (P <0.05). The days of drip bleeding after drug absortion were averages about 8.1 ± 5.0 days for anordrin and the average age was 18.9 ± 19.1 days in the testis group. There was a significant difference between the two groups (P <0.05). Anorene did not occur after transvaginal vaginal administration of heart, liver and kidney function changes.