论文部分内容阅读
16,16—二甲基—Δ~2—前列腺素E_1甲基酯阴道栓剂(代号ONO—802)用于终止早、中期妊娠共117例,76例早期妊娠的流产有效率为77.6%,完全流产率为50%;中期妊娠26例的引产有效率为88.5%,完全流产率为57.7%;15例钳刮术前用以扩张宫口者都收到比较满意的效果。60例(51.3%)于用药过程中有以胃肠道紊乱和低热为主的反应。我们认为本品有可能成为一种终止早、中期妊娠的简便、有效的药物。
A total of 117 cases of early and midterm pregnancy were terminated with 16,16-dimethyl-Δ2-prostaglandin E_1 methyl ester vaginal suppository (code: ONO-802). The effective rate of abortion in 76 cases of early pregnancy was 77.6% The abortion rate was 50%. In the second trimester, the induction rate of labor was 88.5% in 26 cases and the complete abortion rate was 57.7%. All the 15 patients who had dilated uterine cervix before the curettage had satisfactory results. Sixty patients (51.3%) had gastrointestinal disorders and hypocalcemia during the course of medication. We think this product may become an easy and effective drug to terminate early and midterm pregnancy.