论文部分内容阅读
本文调查了９８名铬作业工人，发现尿ＮＡＧ－Ｂ明显升高，尿ＮＡＧ－Ａ显著低于对照组，出现ＮＡＧ－Ａ／ＮＡＧ－Ｂ比值倒置（１：４，正常为３：２）。铬作业工人尿ＮＡＧ－Ｂ在尿蛋白和尿β＿２－ＭＧ均在正常范围时，已开始显著高于对照组，并随肾损害程度加重而明显增加，提示尿ＮＡＧ－Ｂ可能为检测铬性肾损害较灵敏的指标。尿ＮＡＧ－Ａ虽显著低于对照组，但与尿蛋白和尿β＿２－ＭＧ无明显相关关系（ｒ均小于０．１８，Ｐ＞０．０５），提示ＮＡＧ－Ａ显著下降这一特征，似与铬性肾损害无明显关系。但可能为铬接触者健康监测的一个灵敏指标，其机理有待进一步研究。
In this paper, 98 chromium workers were investigated and found that urine NAG-B was significantly elevated and urinary NAG-A was significantly lower than that of the control group, with an NAG-A / NAG-B ratio inversion (1: 4, normal 3: 2). Urine NAG-B in urine of chromium-exposed workers started to be significantly higher than that of control group when urinary protein and urinary β_2-MG were in the normal range, and increased significantly with the degree of renal damage. Urinary NAG-B may be a marker of chrome kidney Damage sensitive indicators. Although NAG-A of urine was significantly lower than that of the control group, it had no significant correlation with urinary protein and urinary β_2-MG (r less than 0.18, P> 0.05), suggesting that NAG-A significantly decreased this feature, There is no significant relationship between chromium and renal damage. But may be a sensitive indicator of health monitoring of chromium contacts, the mechanism remains to be further studied.