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目的揭示血浆血小板膜蛋白CD6 2P对脑梗塞患者血管病变的诊断和预后价值。 方法流式细胞术观察糖尿病与非糖尿病脑梗塞患者CD6 2P的阳性表达率 ,并与健康人作对照。 结果脑梗塞组CD6 2P的阳性表达率高于对照组 (P <0 .0 1) ,且合并有糖尿病组显著高于非糖尿病组 (P <0 .0 1) ;脑梗塞组血小板计数与对照组比较无显著差异。 结论脑梗塞时血小板活化程度明显增高 ,而糖尿病则加剧了这一病理过程的发生。
Objective To reveal the value of plasma platelet membrane protein CD6 2P in the diagnosis and prognosis of vascular lesions in patients with cerebral infarction. Methods The positive rate of CD6 2P expression in diabetic and non-diabetic cerebral infarction patients was observed by flow cytometry and was compared with healthy controls. Results The positive rate of CD6 2P in cerebral infarction group was significantly higher than that in control group (P <0.01), and the level of CD6 2P in cerebral infarction group was significantly higher than that in non-diabetic group (P <0.01) No significant difference between groups. Conclusion The activation of platelet in cerebral infarction is obviously increased, while diabetes aggravates the occurrence of this pathological process.