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用特制装置收集33例鼻咽癌患者治疗前鼻咽部分泌物,以放射免疫法测定其β_2微球蛋白(β_2-MG)含量,并与30例正常人和19例慢性鼻咽炎病人对照。结果发现β_2-MG 均值:鼻咽癌组为4.06±2.01mg/L。慢性鼻咽炎组为1.74±1.04mg/L,正常人组为1.56±0.92mg/L.鼻咽癌组显著高于正常人和慢性鼻咽炎组(P<0.01)。提示鼻咽分泌物中β_2-MG 测定对鼻咽癌早期诊断有参考价值,其临床意义值得进一步探讨。
The nasopharyngeal secretions of 33 patients with nasopharyngeal carcinoma before treatment were collected with a special device. The content of β_2 microglobulin (β_2-MG) was measured by radioimmunoassay and compared with 30 normal controls and 19 chronic nasopharyngitis patients. The results showed that β_2-MG mean: nasopharyngeal carcinoma group was 4.06 ± 2.01mg / L. Chronic nasopharyngitis group was 1.74 ± 1.04mg / L, normal group was 1.56 ± 0.92mg / L. Nasopharyngeal carcinoma group was significantly higher than the normal and chronic nasopharyngitis group (P <0.01). Prompt nasopharyngeal secretions β_2-MG determination of nasopharyngeal carcinoma early diagnosis of reference value, its clinical significance worthy of further exploration.