论文部分内容阅读
目的:探讨长沙地区居民高尿酸血症(HUA)患病率现状及危险因素。方法:采用分层整群抽样方法选取2012年5月至2013年5月长沙地区符合标准的居民2961例,采集居民各项资料,并对2961例居民进行空腹血糖、血脂4项[三酰甘油(TG)、血清总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)]、血尿酸的测定,分析长沙地区高尿酸血症患病率现状及危险因素。结果:(1)2961例居民中,符合HUA诊断标准者共670例,HUA总患病率为22.62%,随着年龄的增大,HUA患病率呈现逐渐上升的趋势,差异具有统计学意义(P<0.01);其中男性HUA患病率为37.68%,高于女性8.50%,差异具有统计学意义(P<0.01);(2)HUA患病的单因素分析结果显示:人均收入、性别、饮酒频率、高血脂、饮食习惯、体力活动频率是影响长沙地区居民HUA患病的单因素,差异具有统计学意义(P<0.001);(3)多因素Logistic回归分析结果显示:男性、饮酒频率、人均收入每月≥5000元、喜甜的饮食习惯、高血脂、体力活动频率均为影响长沙地区居民HUA患病的危险因素,差异具有统计学意义(P<0.001)。结论:长沙地区HUA患病率较高,其中男性患病者多于女性,减少高热量食物的摄入、加强相应体育锻炼、戒酒、合理的控制血脂水平可有效预防HUA。
Objective: To investigate the prevalence and risk factors of hyperuricemia (HUA) in Changsha residents. Methods: A stratified cluster sampling method was used to select 2961 eligible residents in Changsha from May 2012 to May 2013 to collect all the residents’ information, and to investigate the effects of fasting blood glucose, lipids, triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and serum uric acid in Changsha area were analyzed.The prevalence of hyperuricemia And risk factors. Results: (1) Among 2961 residents, 670 patients were diagnosed as HUA, and the prevalence of HUA was 22.62%. The prevalence of HUA showed a gradual upward trend with age, the difference was statistically significant (P <0.01). The prevalence of HUA in male was 37.68%, higher than that in female (8.50%), the difference was statistically significant (P <0.01). (2) The univariate analysis of HUA prevalence showed that per capita income, , Alcohol consumption frequency, hyperlipidemia, dietary habit and physical activity frequency were the single factor influencing HUA prevalence in Changsha residents (P <0.001). (3) Multivariate Logistic regression analysis showed that male, alcohol consumption Frequency, per capita income monthly ≥ 5000 yuan, sweet eating habits, hyperlipidemia, physical activity frequency are influencing Changsha residents HUA risk factors, the difference was statistically significant (P <0.001). Conclusion: The prevalence of HUA in Changsha is higher than that in women, and the incidence of HUA in Changsha is lower than that in women. Therefore, HUA can be effectively prevented by reducing the intake of high-calorie foods, strengthening physical exercise, abstinence and controlling blood lipid levels rationally.