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背景:裸铜结构宫内节育器在铜离子释放过程中含有大量氧化物,容易导致女性出现出血和疼痛等。而纳米铜/低密度聚乙烯复合材料宫内节育器则可以很好地解决以上弊端,有利于维持育龄妇女的生殖健康。目的:分析纳米铜/低密度聚乙烯复合材料宫内节育器对置器后子宫出血、疼痛的影响。方法:将98例自愿要求放置宫内节育器的女性随机均分为两组,观察组放置纳米铜/低密度聚乙烯宫内节育器,对照组放置铜T型220C宫内节育器。放置结束后随访12个月,观察两组不良事件发生情况,包括子宫出血和疼痛等。结果与结论:置器后随访12个月,观察组有1例出现子宫出血,2例患者出现疼痛现象,不良事件发生率为6%;对照组有5例出现子宫出血,8例出现疼痛,不良事件发生率为27%;两组不良事件发生率比较差异有显著性意义(P<0.05)。表明纳米铜/低密度聚乙烯复合材料宫内节育器可有效减少置器后子宫出血和疼痛的出现。
Background: Bare copper intrauterine devices contain a large amount of oxide during the release of copper ions, which easily lead to bleeding and pain in women. The nano-copper / low-density polyethylene IUDs can be a good solution to these shortcomings, will help to maintain the reproductive health of women of childbearing age. Objective: To analyze the effect of nano-Cu / LDPE on uterine hemorrhage and pain after IUD insertion. Methods: Ninety-eight women with voluntary IUD placement were randomly divided into two groups. The observation group was placed with copper nano-copper / LDPE IUD and the control group with copper T-220C intrauterine device. After 12 months of follow-up, the incidence of adverse events in both groups were observed, including bleeding and pain in the uterus. RESULTS AND CONCLUSION: After 12 months of follow-up, there was 1 case of uterine bleeding in the observation group and 2 cases of pain in the observation group. The incidence of adverse events was 6%. In the control group, 5 cases had uterine bleeding and 8 cases had pain, The incidence of adverse events was 27%. There was significant difference between the two groups in the incidence of adverse events (P <0.05). Show that nano-copper / low density polyethylene composite IUD can effectively reduce the occurrence of uterine bleeding and pain after device placement.