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近几年来,抗癫痫新药丙戊酸钠(癫健安)用于临床,控制癫痫大发作效果较好。据报道偶有出现嗜睡、恶心、呕吐、头昏、皮疹等副反应.最近我们发现1例患者,用丙戊酸钠治疗时出现双眼球结膜出血.现报道如下. 患者男性,25岁.从8岁开始全身发硬、口唇发甜、四肢抽搐、双眼凝视、呼之不应,约1min后转醒,醒后意识表现正常,一般每月发作1次,未找医生治疗.于81年起因上述症状复发,次数增加约2-3次/mo,即来我院门诊,诊断为癫痫大发作.用苯妥英钠0.1tid,苯巴比妥30mg tid治疗.由于出现全身皮疹,改用丙戊酸钠0.2tid;后加用扑米酮(扑痫酮)0.25tid治疗,症状发作次数明显
In recent years, anti-epileptic drug valproate (epilepsy) for clinical use, control of epileptic seizures better. It has been reported occasionally lethargy, nausea, vomiting, dizziness, rash and other side effects recently we found that 1 case of patients with sodium valproate treatment of conjunctival hemorrhage occurred when the eyes are as follows. Male patients, 25 years old from At the age of 8, she started to have stiff body, lips and sweetness, convulsions in her limbs, eyes staring, and she should not wake up. After about 1min, she wakes up and awakens her consciousness to normal. She usually attacks once a month without doctor’s treatment. The symptoms of recurrence, the number increased about 2-3 times / mo, that is, to our hospital, diagnosis of epileptic seizures with phenytoin 0.1tid, phenobarbital 30mg tid treatment due to the emergence of systemic rash to valproic acid Sodium 0.2tid; followed by primidone (epilepsy ketone) 0.25tid treatment, the number of symptoms was significantly