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本文联合检测了58例脑胶质瘤EGFR、p53蛋白和PCNA的表达，结果表明，三者的表达率均随胶质瘤的级别升高而增高增强．高级别组与低级别组相比较，有显著差异（P＜0．01），复发组与未复发组相比较．有显著差异（P＜0．01）．提示肿瘤的生物学行为与表达的高低有关，肿瘤的生物学行为越差，表达率就越高．染色强，预后越差。
In this paper, 58 cases of gliomas were detected EGFR, p53 protein and PCNA expression, the results show that the three were all increased with the grade glioma increased and increased. There were significant differences between the high-grade group and the low-grade group (P <0.01), and between the recurrent group and the non-recurrent group. There was a significant difference (P <0.01). Suggesting that the biological behavior of the tumor is related to the level of expression. The worse the biological behavior of the tumor is, the higher the expression rate is. Strong staining, the worse the prognosis.