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[目的]探讨宫颈冷刀锥切术对宫颈上皮内瘤变(CIN)的诊断及治疗作用。[方法]对比126例行宫颈冷刀锥切术和阴道镜下多点活检的CIN患者的病理检查结果,分析CIN患者行宫颈冷刀锥切术的临床疗效和并发症。[结果]阴道镜下多点活检和宫颈冷刀锥切术后病理完全符合83例(占65.9%)。14例(11.1%)患者锥切边缘受累;发现早期浸润癌5例,其中2例早期浸润癌仅行宫颈锥切,随访无复发。宫颈冷刀锥切术的主要并发症为出血和宫颈管狭窄,发生率分别为6.3%(8/126)和3.9%(5/126)。[结论]宫颈锥切术比阴道镜下多点活检对宫颈上皮内瘤变的诊断更准确,并具有重要治疗作用。
[Objective] To investigate the diagnosis and treatment of cervical intraepithelial neoplasia (CIN) by cervical cold knife conization. [Method] Comparing the pathological results of 126 patients with CIN who underwent cold knife conization and colposcopy biopsy, the clinical curative effect and complications of cervical cold knife conization in CIN were analyzed. [Results] 83 cases (65.9%) were pathologically confirmed by colposcopy multi-point biopsy and cervical cold knife conization. In 14 cases (11.1%), the conus margins were involved. In early invasive carcinoma, 5 cases were found. Among them, 2 cases of early invasive carcinoma only had conization of the cervix, and no recurrence was observed. Cervical cold knife conization the main complication of bleeding and cervical stenosis, the incidence was 6.3% (8/126) and 3.9% (5/126). [Conclusion] Cervical conization is more accurate than cervical colposcopy biopsy for the diagnosis of cervical intraepithelial neoplasia, and has an important therapeutic effect.