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他汀类药物是临床广泛应用的调血脂药,用于高胆固醇血症和动脉粥样硬化等疾病的治疗,近年来的研究证明他汀类药物是有效预防和治疗心血管疾病的一级、二级药物。调查显示[1],我国血脂控制达标率与指南的要求存在很大差距,特别是高危和极高危患者,明显低于国外调查。因此,应该积极在临床上推广使用他汀类药物。他汀类药物不良反应较多,相互作用较复杂,患者用药依从性差,临床药师应在该类药物应用中做好药学监护工作。
Statins are widely used in clinical lipid-lowering drugs for the treatment of hypercholesterolemia and atherosclerosis and other diseases, recent studies have shown that statin drugs are effective in the prevention and treatment of cardiovascular disease, a drug. Survey [1], our blood lipid control compliance rate and the guidelines there is a big gap, especially in high-risk and very high-risk patients, significantly lower than the survey abroad. Therefore, we should actively promote the clinical use of statins. More side effects of statin drugs, the interaction is more complex, poor compliance of patients with medication, clinical pharmacists should be in the application of such drugs in pharmacy care.