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目的观察机械通气下顺苯磺酸阿曲库铵联合咪达唑仑治疗重度破伤风临床疗效。方法回顾性分析31例重度破伤风患者的临床资料,观察患者治愈情况。结果治疗后27例破伤风患者情况好转,治愈率87.10%,随访观察患者恢复情况良好,神志清醒,略有四肢乏力,无其他不良反应情况发生;4例(12.90%)患者因肌肉持续痉挛、心率快、心力衰竭原因死亡。结论机械通气下顺苯磺酸阿曲库铵联合咪达唑仑治疗重度破伤风疗效显著且安全性高,值得临床运用与推广。
Objective To observe the clinical efficacy of atracurium sulfmate combined with midazolam in the treatment of severe tetanus under mechanical ventilation. Methods The clinical data of 31 patients with severe tetanus were retrospectively analyzed to observe the cure of patients. Results After treatment, the incidence of tetanus in 27 cases improved, the cure rate was 87.10%. The follow-up observation showed that the patients recovered well and were conscious, with slight limb weakness and no other adverse reactions. In 4 cases (12.90% Heart rate, heart failure causes death. Conclusion Mechanical ventilation with atracurium cisplatin combined with midazolam in the treatment of severe tetanus has obvious curative effect and high safety, which is worthy of clinical application and promotion.