本文研究了家兔抗小白鼠胸腺细胞血清的体内外活性。在体外有凝集胸腺细胞的作用;在体内对淋巴器官有明显的免疫抑制作用,包括降低周围血液白血球,胸腺的萎缩及胸腺细胞的排空;脾,淋巴结胸腺依赖区淋巴细胞选择性减少。 进一步证实ATS在移植中的作用。ATS方法可常规应用于细胞株致癌性的鉴定。由于ATS方法简单,重复性强,诱发肿瘤时间短,值得推广。 In this paper, the activity of rabbit anti-mice thymocyte serum in vitro and in vivo was studied. In vitro has the effect of agglutination of thymocytes; it has obvious immunosuppressive effects on lymphoid organs in vivo, including reduction of peripheral blood leukocytes, atrophy of thymus, and emptying of thymocytes; selective reduction of lymphocytes in the thymus-dependent region of the spleen and lymph nodes. Further confirm the role of ATS in transplantation. The ATS method can be routinely applied to the identification of the carcinogenicity of cell lines. Because the ATS method is simple, reproducible, and the tumor-inducing time is short, it is worth promoting.